Placeholder: Immune cell expressing PD1 interacted with Cancer cell expressing PD-L1 Immune cell expressing PD1 interacted with Cancer cell expressing PD-L1

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Immune cell expressing PD1 interacted with Cancer cell expressing PD-L1

11 months ago

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Kandinsky 2.2

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7

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Immune cells expressing PD1 interacted with Cancer cell expressing PDL-1
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With immune checkpoint inhibitor therapy: Antibody binds to PD-1 or PD-L1 receptor Blocks interaction between PD-1 and PD-L1 Remove brakes on T cell activation Result: T cell fully activates upon tumor antigen recognition T cell divides and proliferates T cell releases cytokines and cytotoxic granules Tumor cell killed by immune response Unleashes anti-tumor immunity)
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